Members

Staff

  • Professor

    Shinsuke Ishigaki

    shinsuke@belle.shiga-med.ac.jp

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    Comment
    The goal of our lab is to elucidate the pathogenesis of neurological diseases and develop therapeutics and diagnostic biomarkers for them. Our current interests include FTLD, tauopathies, and Alzheimer’s disease as well as RNA metabolism, neural circuits, and behavior alteration.
  • Associate Professor

    Daijiro Yanagisawa

    daijiroy@belle.shiga-med.ac.jp

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  • Assistant Professor

    Yusuke Fujioka

    yusukyf@belle.shiga-med.ac.jp

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  • Special Contract Assistant Professor

    Yuri Kim

    yuki936@belle.shiga-med.ac.jp

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  • Special Contract Assistant Professor

    Moniruzzaman Mohammad

    mmonir@belle.shiga-med.ac.jp

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    Comment
    RNA binding protein Fused in sarcoma (FUS) undergoes liquid-liquid phase separation (LLPS), resembling oil in vinegar. Evidence suggested that phase separation of FUS is crucially involved in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) pathogenesis and RNA regulates its droplet formation, suggesting that antisense oligos (ASOs) modulating FUS LLPS could be a promising drug candidate against ALS/FTLD. My efforts are designed to develop oligonucleotide drugs targeting phase separation for ALS/FTLD using a combination of biochemical and cellular technologies including iPSC-derived motor neurons and animal models.

Technical Assistant

Student

  • Graduate Students

    Asraa Faris Abdulridha Aldoghachi

    asraa@belle.shiga-med.ac.jp

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    Comment
    Asraa Faris is a second year PhD student at the Molecular Neuroscience Reseach Center. Her research project focuses on targeting thioredoxin interacting protein for the treatment of diabetes mellitus.
  • Undergraduate

    Risa Chichiishi

  • Graduate Students

    Guo Xiaokai

    gxkjj@belle.shiga-med.ac.jp

    Comment
    Participated in medical activities on the snow track for the 2022 Beijing Winter Olympics and Winter Paralympics.
  • Undergraduate

    Yuika Kinoshita

  • Undergraduate

    Yuina Konaka

  • Research Student

    Nguyen Tran Minh Duc

    minhduc@belle.shiga-med.ac.jp

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    Comment
    Neurologist, researcher, ALS caregiver and founder of ALS Vietnam
  • Research Student

    Ankhbayar Munkh-Erdene

    munkh314@belle.shiga-med.ac.jp

    Comment
    "Someone who wants to understand biotic existence of layer of the human brain"
  • Undergraduate

    Kenji Akiyoshi