Staff
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Professor
Shinsuke Ishigaki
shinsuke@belle.shiga-med.ac.jp
- Google Scholar
- https://scholar.google.co.jp/citations?user=ua4EnpcyC3cC&hl
- @IshigakiLab
- Comment
- The goal of our lab is to elucidate the pathogenesis of neurological diseases and develop therapeutics and diagnostic biomarkers for them. Our current interests include FTLD, tauopathies, and Alzheimer’s disease as well as RNA metabolism, neural circuits, and behavior alteration.
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Special Contract Assistant Professor
Moniruzzaman Mohammad
- Comment
- RNA binding protein Fused in sarcoma (FUS) undergoes liquid-liquid phase separation (LLPS), resembling oil in vinegar. Evidence suggested that phase separation of FUS is crucially involved in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) pathogenesis and RNA regulates its droplet formation, suggesting that antisense oligos (ASOs) modulating FUS LLPS could be a promising drug candidate against ALS/FTLD. My efforts are designed to develop oligonucleotide drugs targeting phase separation for ALS/FTLD using a combination of biochemical and cellular technologies including iPSC-derived motor neurons and animal models.
Graduate Student (PhD Course)
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Graduate Students
Asraa Faris Abdulridha Aldoghachi
- Comment
- Asraa Faris is a second year PhD student at the Molecular Neuroscience Reseach Center. Her research project focuses on targeting thioredoxin interacting protein for the treatment of diabetes mellitus.
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Graduate Students
Guo Xiaokai
- Comment
- Participated in medical activities on the snow track for the 2022 Beijing Winter Olympics and Winter Paralympics.
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Graduate Student
Nguyen Tran Minh Duc
- Comment
- Neurologist, researcher, ALS caregiver and founder of ALS Vietnam
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Graduate Student
Ankhbayar Munkh-Erdene
munkh314@belle.shiga-med.ac.jp
- Comment
- "Someone who wants to understand biotic existence of layer of the human brain"
