- We study the pathogenesis of neuronal disorders
to develop therapeutics and biomarkers
for neurodegenerative and dementia diseases. - Our current interests include molecular and neuronal function,
neuronal circuit alteration, and behavior impairments,
involved in amyotrophic lateral sclerosis (ALS),
frontotemporal lobar degeneration (FTLD), tauopathies, and Alzheimer’s disease.
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- Elucidation of pathomechanisms of frontotemporal lobar degeneration (FTLD) spectrum disorders including FTLD, amyotrophic lateral sclerosis (ALS), and other tauopathies.
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- Investigation of molecular function of FUS and tau using animal models.
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- Development of novel biomarkers focusing on higher brain dysfunction observed in FTLD.
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- Development of oligonucleotide therapeutics based on the molecular functions of FUS and tau.
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- Development of next-generation imaging diagnostic methods for Alzheimer’s disease.
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- Development of diagnostics and therapeutics for Alzheimer’s disease.
- Publications
- This section introduces major research achievements such as academic papers published so far.
News
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- 2022.10.31Information
- Website has been renewed.