Elucidation of pathomechanisms of frontotemporal lobar degeneration (FTLD) spectrum disorders including FTLD, amyotrophic lateral sclerosis (ALS), and other tauopathies.

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Investigation of molecular function of FUS and tau using animal models.

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Development of novel biomarkers focusing on higher brain dysfunction observed in FTLD.

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Development of oligonucleotide therapeutics based on the molecular functions of FUS and tau.

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Development of next-generation imaging diagnostic methods for Alzheimer's disease.

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Development of diagnostics and therapeutics for Alzheimer's disease.

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