業績

2017年

* corresponding author; # equally contributed author

  1. Ishigaki, S.*,#, Fujioka, Y.#, Okada, Y., Riku, Y., Udagawa, T., Honda, D., Yokoi, S., Endo, K., Ikenaka, K., Takagi, S., Iguchi, Y., Sahara, N., Takashima, A., Okano, H., Yoshida, M., Warita, H., Aoki, M., Watanabe, H., Okado, H., Katsuno, M., and Sobue, G., Altered Tau Isoform Ratio Caused by Loss of FUS and SFPQ Function Leads to FTLD-like Phenotypes. Cell Rep, 18: 1118-1131, 2017.

  2. Yokoi, S., Udagawa, T., Fujioka, Y., Honda, D., Okado, H., Watanabe, H., Katsuno, M., Ishigaki, S.*, and Sobue, G., 3’UTR Length-Dependent Control of SynGAP Isoform alpha2 mRNA by FUS and ELAV-like Proteins Promotes Dendritic Spine Maturation and Cognitive Function. Cell Rep, 20: 3071-3084, 2017.

  3. Riku, Y., Watanabe, H., Yoshida, M., Mimuro, M., Iwasaki, Y., Masuda, M., Ishigaki, S., Katsuno, M., and Sobue, G., Pathologic Involvement of Glutamatergic Striatal Inputs From the Cortices in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis. J Neuropathol Exp Neurol, 76: 759-768, 2017.

  4. Ogawa, T., Irikawa, N., Yanagisawa, D., Shiino, A., Tooyama, I., and Shimizu, T. Taste detection and recognition thresholds in Japanese patients with Alzheimer-type dementia. Auris Nasus Larynx, 44: 168–173, 2017.

  5. Kitamura, Y., Inden, M., Kimoto, Y., Takata, K., Yanagisawa, D., Hijioka, M., Ashihara, E., Tooyama, I., Shimohama, S., and Ariga, H. Effects of a DJ-1-binding compound on spatial learning and memory impairment in a mouse model of Alzheimer’s disease. J Alzheimers Dis, 55: 67–72, 2017.

  6. Ibrahim, N.F., Yanagisawa, D., Durani, L.W., Hamezah, H.S., Damanhuri, H.A., Wan Ngah, W.Z., Tsuji, M., Kiuchi, Y., Ono, K., and Tooyama, I. Tocotrienol-rich fraction modulates amyloid pathology and improves cognitive function in AβPP/PS1 mice. J Alzheimers Dis, 55: 597–612, 2017.

  7. Hijioka, M., Inden, M., Yanagisawa, D., and Kitamura, Y. DJ-1/PARK7: A New Therapeutic Target for Neurodegenerative Disorders. Biol Pharm Bull, 40: 548–552, 2017.

  8. Hamezah, H.S., Durani, L.W., Ibrahim, N.F., Yanagisawa, D., Kato, T., Shiino, A., Tanaka, S., Damanhuri, H.A., Ngah, W.Z.W., and Tooyama, I. Volumetric changes in the aging rat brain and its impact on cognitive and locomotor functions. Exp Gerontol, 99: 69–79, 2017.

  9. Guan, H., Yang, H., Yang, M., Yanagisawa, D., Bellier, J.P., Mori, M., Takahata, S., Nonaka, T., Zhao, S., and Tooyama, I. Mitochondrial ferritin protects SH-SY5Y cells against H2O2-induced oxidative stress and modulates α-synuclein expression. Exp Neurol, 291: 51–61, 2017.

  10. Durani, L.W., Hamezah, H.S., Ibrahim, N.F., Yanagisawa, D., Makpol, S., Damanhuri, H.A., and Tooyama, I. Age-related changes in the metabolic profiles of rat hippocampus, medial prefrontal cortex and striatum. Biochem Biophys Res Commun, 493: 1356–1363, 2017.

  11. Yanagisawa, D., Oda, K., Inden, M., Morikawa, S., Inubushi, T., Taniguchi, T., Hijioka, M., Kitamura, Y., and Tooyama, I. Fluorodopa is a promising fluorine-19 MRI probe for evaluating striatal dopaminergic function in a rat model of Parkinson’s disease. J Neurosci Res, 95: 1485–1494, 2017.