業績

2021年

* corresponding author; # equally contributed author

  1. Riku, Y., Seilhean, D., Duyckaerts, C., Boluda, S., Iguchi, Y., Ishigaki, S., Iwasaki, Y., Yoshida, M., Sobue, G., and Katsuno, M., Pathway from TDP-43-Related Pathology to Neuronal Dysfunction in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration. Int J Mol Sci, 22, 3843, 2021.

  2. Yanagisawa, D. #, Kato, T. #, Taguchi, H., Shirai, N., Hirao, K., Sogabe, T., Tomiyama, T., Gamo, K., Hirahara, Y., Kitada, M., and Tooyama, I. Keto form of curcumin derivatives strongly binds to Aβ oligomers but not fibril. Biomaterials, 270: 120686, 2021.

  3. Yanagisawa, D.*, Ibrahim, N.F., Taguchi, H., Morikawa, S., Tomiyama, T., and Tooyama, I*. Fluorine-19 magnetic resonance imaging for detection of amyloid β oligomers using a keto form of curcumin derivative in a mouse model of Alzheimer’s disease. Molecules, 26: 1362, 2021.

  4. Yanagisawa, D.*, Hamezah, H.S., Pahrudin Arrozi, A., and Tooyama, I*. Differential accumulation of tau pathology between reciprocal F1 hybrids of rTg4510 mice. Sci Rep, 11: 9623, 2021.

  5. Yamaguchi, N., Sawano, T., Fukumoto, K., Nakatani, J., Inoue, S., Doe, N., Yanagisawa, D., Tooyama, I., Nakagomi, T., Matsuyama, T., and Tanaka, H. Voluntary running exercise after focal cerebral ischemia ameliorates dendritic spine loss and promotes functional recovery. Brain Res, 1767: 147542, 2021.

  6. Pahrudin Arrozi, A., Yanagisawa, D., Kato, T., Akatsu, H., Hashizume, Y., Kaneda, D., and Tooyama, I. Nasal extracts from patients with Alzheimer’s disease induce aggregates in a cellular model of tau propagation. J Alzheimers Dis Rep, 5:263-274, 2021.

  7. Pahrudin Arrozi, A., Abu Bakar, Z.H., Taguchi, H., Yanagisawa D.*, and Tooyama, I*. A fluorine-19 magnetic resonance probe, Shiga-Y5, downregulates thioredoxin-interacting protein expression in the brain of a mouse model of Alzheimer’s disease. Molecules, 26: 5342, 2021.

  8. Ibrahim, N.F., Hamezah, H.S., Yanagisawa D.*, Tsuji, M., Kiuchi, Y., Ono, K., and Tooyama, I*. N Tocotrienols inhibit amyloid-β aggregation and disaggregate preformed fibrils. Biochem Biophys Rep, 28:101131, 2021.

  9. Abu Bakar Z.H., Kato, T., Yanagisawa, D., Bellier, J.P., Mukaisho, K., and Tooyama, I. Immunohistochemical study of mitochondrial ferritin in the midbrain of patients with progressive supranuclear palsy. Acta Histochem Cytochem, 54: 97-104, 2021.